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Anti-PAI-1 Antibody (2X285)
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Catalog No. TMAH-01085
Alias SERPINE1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, PLANH1, PAI-1, PAI1, PAI
Anti-PAI-1 Antibody (2X285) is an antibody targeting PAI-1. Anti-PAI-1 Antibody (2X285) can be used in ELISA, WB, IHC.
Anti-PAI-1 Antibody (2X285)
Anti-PAI-1 Antibody (2X285)
😃Good
Catalog No. TMAH-01085Alias SERPINE1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, PLANH1, PAI-1, PAI1, PAI
Anti-PAI-1 Antibody (2X285) is an antibody targeting PAI-1. Anti-PAI-1 Antibody (2X285) can be used in ELISA, WB, IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | 198 € | 7-10 days | |
| 100 μL | 331 € | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Monoclonal Application: ELISA, WB, IHC Reactivity: Human |
| Alias | SERPINE1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, PLANH1, PAI-1, PAI1, PAI |
| Ig Type | Rabbit IgG |
| Clone | 2X285 |
| Reactivity | Human |
| Verified Activity | 1. Western Blot -Positive WB detected in: U-251 whole cell lysate, U-87 whole cell lysate -All lanes: PAI1 Antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 46, 44 kDa -Observed band size: 45 kDa 2. IHC image of TMAH-01085 diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB. |
| Application | ELISA, WB, IHC |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading. Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human PAI1 |
| Antigen Species | Human |
| Gene ID | 5054 |
| Uniprot ID | |
| Biology Area | Cancer, Cardiovascular, Cell biology, Metabolism |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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