Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase. Topoisomerase I inhibitor 3 is an inhibitor of topoisomerase I that interact with topoisomerase I-DNA complex [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,520.00 | |
50 mg | 6-8 weeks | $ 1,980.00 | |
100 mg | 6-8 weeks | $ 2,500.00 |
Description | Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase. Topoisomerase I inhibitor 3 is an inhibitor of topoisomerase I that interact with topoisomerase I-DNA complex [1]. |
In vitro | Topoisomerase I inhibitor 3 (Compound ZML-14) exhibits cytotoxic effects, demonstrating IC50 values of 1.94 ± 0.09 μM for HepG2, 10.32 ± 0.39 μM for A2780, 13.1 ± 0.96 μM for HeLa, 40.69 ± 5.36 μM for HCT116, 28.11 ± 2.50 μM for SW1990, >100 μM for MCF7, and 37.42 ± 2.05 μM for L-02 cells, respectively [1]. |
Molecular Weight | 311.31 |
Formula | C18H14FNO3 |
CAS No. | 2588211-50-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Topoisomerase I inhibitor 3 2588211-50-9 inhibitor inhibit