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CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated

(Synonyms: tumor necrosis factor receptor superfamily, member 8, Ki-1, D1S166E, CD30) Copy Product Info

Synonyms: tumor necrosis factor receptor superfamily, member 8, Ki-1, D1S166E, CD30

Catalog No. TMPY-05118 Copy Product Info
CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.9 kDa and the accession number is P28908-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$1127-10 days7-10 days
10 µg$1837-10 days7-10 days
20 µg$3067-10 days7-10 days
50 µg$4927-10 days7-10 days
100 µg$8427-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.9 kDa and the accession number is P28908-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP28908-1
ConstructionA DNA sequence encoding the TNFRSF8 (NP_001234.2) (Met1-Lys379) was expressed with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro. Predicted N terminal: Phe 19
Protein Purity
> 90 % as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing Sterile PBS. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonymstumor necrosis factor receptor superfamily, member 8, Ki-1, D1S166E, CD30
Research Background
CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor (TNFR) superfamily. CD30 protein is expressed by activated, but not resting, T and B cells. CD30 can regulate proliferation of lymphocytes and may also play an important role in human immunodeficiency virus replication. As a regulator of apoptosis, CD30 protein induces cell death or proliferation, depending on the cell type, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. CD30 protein expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs), and CD30 is also linked to leukocytes in patients with chronic inflammatory diseases, including lupus erythematosus, asthma, rheumatoid arthritis and atopic dermatitis (AD).Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Chemical Properties
Molecular Weight39.9 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated chemical structure | CD30/TNFRSF8 Protein, Human, Recombinant (His), Biotinylated molecular weight