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Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody 2 (Synonyms: S6K-alpha-1, S6K alpha 1, RSK1p90, RSK1, RSK ...)

Catalog No. TMAC-03039 Copy Product Info
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Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA1 (Thr573). Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAC-03039
Synonyms S6K-alpha-1, S6K alpha 1, RSK1p90, RSK1, RSK 1 p90, RSK 1, RSK, RPS6KA1 (p-Thr573), RPS6KA1 (p-T573), rps6ka, RPS6K1 alpha, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase polypeptide 1, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase 90kD polypeptide 1, ribosomal protein S6 kinase, p-RPS6KA1 (Thr573), p-RPS6KA1 (T573), pp90RSK1, polypeptide 1, Phospho-RPS6KA1 (T573), p90S6K, p90RSK1, p90 RSK1, OTTHUMP00000004113, Mitogen-activated protein kinase-activated protein kinase 1A, MGC79981, MAPKAPK-1a, MAPKAPK1A, MAPKAP kinase 1a, MAP kinase activated protein kinase 1a, KS6A1_HUMAN, HU1, HU 1, EC 2.7.11.1, dJ590P13.1, 90kD, 90 kDa ribosomal protein S6 kinase 1

Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA1 (Thr573). Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-RPS6KA1
(Thr573) Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2167-10 days7-10 days
100 μL$3187-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA1 (Thr573). Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody can be used in IHC,WB.
SynonymsS6K-alpha-1, S6K alpha 1, RSK1p90, RSK1, RSK 1 p90, RSK 1, RSK, RPS6KA1 (p-Thr573), RPS6KA1 (p-T573), rps6ka, RPS6K1 alpha, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase polypeptide 1, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase 90kD polypeptide 1, ribosomal protein S6 kinase, p-RPS6KA1 (Thr573), p-RPS6KA1 (T573), pp90RSK1, polypeptide 1, Phospho-RPS6KA1 (T573), p90S6K, p90RSK1, p90 RSK1, OTTHUMP00000004113, Mitogen-activated protein kinase-activated protein kinase 1A, MGC79981, MAPKAPK-1a, MAPKAPK1A, MAPKAP kinase 1a, MAP kinase activated protein kinase 1a, KS6A1_HUMAN, HU1, HU 1, EC 2.7.11.1, dJ590P13.1, 90kD, 90 kDa ribosomal protein S6 kinase 1
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of extracts from 293 cells treated with UV using p90 RSK (Phospho-Thr573) Antibody TMAC-03039. The lane on the right is treated with the antigen-specific peptide.
2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p90 RSK (Phospho-Thr573) antibody TMAC-03039 (left) or the same antibody preincubated with blocking peptide (right).
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundSerine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 573(L-M-T(p)-P-C) derived from Human p90 RSK
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 95 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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