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Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody 2

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Catalog No. TMAC-03039

Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA1 (Thr573). Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody can be used in WB,IHC.

Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody 2

Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody 2

😃Good
Catalog No. TMAC-03039
Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA1 (Thr573). Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA1 (Thr573). Anti-Phospho-RPS6KA1 (Thr573) Polyclonal Antibody can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundSerine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 573(L-M-T(p)-P-C) derived from Human p90 RSK
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 95 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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