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IL-17RD Protein, Mouse, Recombinant (His)

Catalog No. TMPJ-01216
Synonyms: Sef, mSef, Interleukin-17 receptor-like protein, Il17rlm, Interleukin-17 receptor D, IL-17 receptor D, Il17rd, IL-17RD

The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development.

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IL-17RD Protein, Mouse, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 107.00
50 μg 5 days $ 324.00
500 μg 5 days $ 1,950.00
1 mg 5 days $ 2,940.00
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Biological Description
Technical Params
Product Properties
Description The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development.
Species Mouse
Expression System Human Cells
Tag C-6His
Accession Number Q8JZL1
Synonyms Sef, mSef, Interleukin-17 receptor-like protein, Il17rlm, Interleukin-17 receptor D, IL-17 receptor D, Il17rd, IL-17RD
Amino Acid Cys17-Arg299
Construction Recombinant Mouse Interleukin-17 receptor D is produced by our Mammalian expression system and the target gene encoding Cys17-Arg299 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 40-65 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development.

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Keywords

IL-17RD Protein, Mouse, Recombinant (His) Sef mSef Interleukin-17 receptor-like protein Il17rlm Interleukin-17 receptor D IL-17 receptor D Il17rd IL-17RD recombinant recombinant-proteins proteins protein

 

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