The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 107.00 | |
50 μg | 5 days | $ 324.00 | |
500 μg | 5 days | $ 1,950.00 | |
1 mg | 5 days | $ 2,940.00 |
Description | The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development. |
Species | Mouse |
Expression System | Human Cells |
Tag | C-6His |
Accession Number | Q8JZL1 |
Synonyms | Sef, mSef, Interleukin-17 receptor-like protein, Il17rlm, Interleukin-17 receptor D, IL-17 receptor D, Il17rd, IL-17RD |
Amino Acid | Cys17-Arg299 |
Construction | Recombinant Mouse Interleukin-17 receptor D is produced by our Mammalian expression system and the target gene encoding Cys17-Arg299 is expressed with a 6His tag at the C-terminus. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 40-65 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | The Il17rd gene encodes a transmembrane protein of the IL-17 receptor family. IL-17RD, originally termed similar expression to fibroblast growth factor (fgf) genes (Sef) as it belonged to the FGF synexpression group in zebrafish development, is the only orphan receptor without any known ligand within the IL-17R family. IL-17RD is a transmembrane protein shown to inhibit fibroblast growth factor signaling in developmental and cancer contexts, however its role as a tumor suppressor remains to be fully elucidated. The full-length IL-17 RD isoform is expressed in most adult tissues and during embryonic development. |
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IL-17RD Protein, Mouse, Recombinant (His) Sef mSef Interleukin-17 receptor-like protein Il17rlm Interleukin-17 receptor D IL-17 receptor D Il17rd IL-17RD recombinant recombinant-proteins proteins protein