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Anti-IL-11 Polyclonal Antibody (Synonyms: interleukin 11)

Catalog No. TMAB-00940 Copy Product Info
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Anti-IL-11 Polyclonal Antibody is a Rabbit antibody targeting IL-11. Anti-IL-11 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.

Anti-IL-11 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-00940
Synonyms interleukin 11

Anti-IL-11 Polyclonal Antibody is a Rabbit antibody targeting IL-11. Anti-IL-11 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.

Anti-IL-11 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-11 Polyclonal Antibody is a Rabbit antibody targeting IL-11. Anti-IL-11 Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
Synonymsinterleukin 11
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human,Dog,Pig,Cow,GuineaPig)
Verified Activity
1. Sample: Testis (Mouse) Lysate at 30 μg
Primary: Anti-IL-11 (TMAB-00940) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/10000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa
2. Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (IL-11) Polyclonal Antibody, Unconjugated (TMAB-00940) at 1:400 overnight at 4°C, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0); Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30 min; Antibody incubation with (IL-11) Polyclonal Antibody, Unconjugated (TMAB-00940) at 1:400 overnight at 4°C, followed by conjugation to the secondary antibody (labeled with HRP) and DAB staining.
4. Sample:
Lane 1: Mouse Kidney tissue lysates
Lane 2: Rat Kidney tissue lysates
Primary: Anti-IL-11 (TMAB-00940) at 1/500 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 19 kDa
Observed band size: 19 kDa
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundInterleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IL-11
Antigen Species
Human
Gene Name
IL11
Gene ID
Protein Name
Interleukin-11
Uniprot ID
Biology Area
Interleukins,Interleukin,Non-CD,Interleukins,Other secreted molecules,Thrombocytic Lineage
Function
Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production.
Chemical Properties
Molecular WeightTheoretical: 19 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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