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Didesethyl chloroquine

Name: Didesethyl chloroquine
Brand: TargetMol
SKU: T11039
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11039Cas No. 4298-14-0

Alias Bisdesethylchloroquine

Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of the antimalarial drug chloroquine.

Didesethyl chloroquine

🥰Excellent

Purity: 97.91%

Catalog No. T11039Alias BisdesethylchloroquineCas No. 4298-14-0

Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of the antimalarial drug chloroquine.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$53	In Stock	In Stock
5 mg	$133	In Stock	In Stock
10 mg	$197	In Stock	In Stock
25 mg	$331	In Stock	In Stock
50 mg	$472	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:97.91%

Appearance:Solid

Color:Yellow

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Didesethyl chloroquine (Bisdesethylchloroquine) is an effective myocardial inhibitor. Didesethyl chloroquine (Bisdesethylchloroquine) is the main metabolite of the antimalarial drug chloroquine.
Targets&IC50	P. falciparum (K1):1.3386 μM, P. falciparum (HB3):0.0472 μM, P. falciparum (PH3):1.2563 μM, P. falciparum (3D7):0.0553 μM, P. falciparum:58.3 μM
Synonyms	Bisdesethylchloroquine

Chemical Properties

Molecular Weight	263.77
Formula	C₁₄H₁₈ClN₃
Cas No.	4298-14-0
Smiles	CC(CCCN)Nc1ccnc2cc(Cl)ccc12
Relative Density.	1.208g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (341.21 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7912 mL	18.9559 mL	37.9118 mL	189.5591 mL
5 mM	0.7582 mL	3.7912 mL	7.5824 mL	37.9118 mL
10 mM	0.3791 mL	1.8956 mL	3.7912 mL	18.9559 mL
20 mM	0.1896 mL	0.9478 mL	1.8956 mL	9.4780 mL
50 mM	0.0758 mL	0.3791 mL	0.7582 mL	3.7912 mL
100 mM	0.0379 mL	0.1896 mL	0.3791 mL	1.8956 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc