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Anti-Aminopeptidase N/CD13 Antibody (9P935)
😃Good
Catalog No. TMAY-00186
Alias P150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase
Anti-Aminopeptidase N/CD13 Antibody (9P935) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (9P935) can be used in IHC-P.
Anti-Aminopeptidase N/CD13 Antibody (9P935)
Anti-Aminopeptidase N/CD13 Antibody (9P935)
😃Good
Catalog No. TMAY-00186Alias P150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase
Anti-Aminopeptidase N/CD13 Antibody (9P935) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (9P935) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | 255 € | 7-10 days |
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Chemical Properties
| Description | Anti-Aminopeptidase N/CD13 Antibody (9P935) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (9P935) can be used in IHC-P. |
| Alias | P150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9P935 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human ANPEP in human kidney with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. 2. Immunochemical staining of human ANPEP in human hepatoma with rabbit monoclonal antibody at 1:200 dilution, formalin-fixed paraffin embedded sections. |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD13/ANPEP (rh CD13/ANPEP; TMPY-00665; NP_001141.2; Lys69-Lys967,603Met/Ile). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 family. CD13 plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases and is involved in the metabolism of regulatory peptides by diverse cell types. CD13/APN is a potent regulator of angiogenesis which is essential for tumor invasion and metastasis, and its transcription in activated endothelial cells is induced by angiogenic growth factors via the RAS/MAPK pathway. In addition, this enzyme has been shown to participate in antigen processing and presentation, and accordingly, defects in this gene appear to be a cause of various types of leukemia or lymphoma and carcinomas. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CD13/ANPEP Protein (TMPY-00665) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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