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Synonyms: Transforming growth factor β-2, Transforming growth factor beta-2, TGF-β-2, TGF-β2, TGF-beta-2, TGFB2, Polyergin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Cetermin, BSC-1 cell growth inhibitor
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-TGF beta 2 Polyclonal Antibody is a Rabbit antibody targeting TGF beta 2. Anti-TGF beta 2 Polyclonal Antibody can be used in WB. |
| Synonyms | Transforming growth factor β-2, Transforming growth factor beta-2, TGF-β-2, TGF-β2, TGF-beta-2, TGFB2, Polyergin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Cetermin, BSC-1 cell growth inhibitor |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1 mg/mL |
| Research Background | Transforming growth factor beta s (TGF beta s) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGF Alpha. It is now realized that TGF beta s mediate many cell-cell interactions that occur during embryonic development. Three TGF beta s have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGF beta requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGF beta 3 protein has approximately 80% identity to the mature region of both TGF beta 1 and TGF beta 2. However, the NH2 terminals or precursor regions of their molecules share only 27% sequence identity. |
| Immunogen | KLH conjugated synthetic peptide: human TGF beta 2 |
| Antigen Species | Human |
| Gene Name | TGFB2 |
| Gene ID | |
| Protein Name | Transforming growth factor beta-2 proprotein |
| Uniprot ID | |
| Biology Area | Response to hypoxia,TGF,Angiogenic growth factors,Hypoxia,TGF,Secreted |
| Function | TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth. |
| Molecular Weight | Theoretical: 50 kDa. Actual: 48-50 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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