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Anti-THAP11 Antibody (8P657)
(Synonyms: THAP domain-containing protein 11, THAP domain containing 11, Thap 11, THA11_HUMAN, RONIN, HRIHFB2206, CTG B45d, CTG B43a) Copy Product Info
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Synonyms: THAP domain-containing protein 11, THAP domain containing 11, Thap 11, THA11_HUMAN, RONIN, HRIHFB2206, CTG B45d, CTG B43a
Catalog No. TMAC-04028 Copy Product Info
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Anti-THAP11 Antibody (8P657) is a Mouse antibody targeting THAP11. Anti-THAP11 Antibody (8P657) can be used in FCM,ICC,IHC,WB.
Anti-THAP11 Antibody
(8P657)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $296 | 7-10 days | 7-10 days | |
| 100 µL | $428 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-THAP11 Antibody (8P657) is a Mouse antibody targeting THAP11. Anti-THAP11 Antibody (8P657) can be used in FCM,ICC,IHC,WB. |
| Synonyms | THAP domain-containing protein 11, THAP domain containing 11, Thap 11, THA11_HUMAN, RONIN, HRIHFB2206, CTG B45d, CTG B43a |
| Clone | 8P657 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of THAP11 on Hela (1) and NTERA-2 (2) cell lysate using anti-THAP11 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-THAP11 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human ovary cancer tissue using anti-THAP11 antibody. Counter stained with hematoxylin. 4. ICC staining THAP11 (green) and actin filaments (red) in NTERA-2 cells. Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of Hela cells with THAP11 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple).  , , , , |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC: 1:100-500; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Research Background | Members of the THAP (thanatos-associated protein) family of proteins contain a well conserved DNA-binding domain known as the THAP-type zinc finger motif. Proteins containing the THAP-type zinc finger motif are commonly involved in transcriptional regulation, cell-cycle control, apoptosis and chromatin modification. The THAP-type zinc finger domain is suggested to have similarities with the site-specific DNA-binding domain (DBD) of Drosophila P element transposase. THAP11 (THAP domain containing 11), also known as HRIHFB2206, is a 314 amino acid protein that belongs to the THAP11 family and contains one THAP-type zinc finger. Localizing to the nucleus and cytoplasm, THAP11 may act as a transcriptional repressor, playing a role in embryogenesis and pluripotency of embryonic stem cells by recruiting epigenetic modifiers. THAP11 interacts with HCF1 via a coiled coil domain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 45, 75 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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