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Compound A6, a potent and selective PROTAC HDAC6 degrader, exhibits a DC50 of 3.5 nM. It demonstrates notable antiproliferative activity by inducing apoptosis in myeloid leukemia cell lines [1].

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| Description | Compound A6, a potent and selective PROTAC HDAC6 degrader, exhibits a DC50 of 3.5 nM. It demonstrates notable antiproliferative activity by inducing apoptosis in myeloid leukemia cell lines [1]. |
| Targets&IC50 | HDAC1:0.1 μM, HDAC6:4.86 nM, HDAC6:3.5 nM (DC50) |
| Molecular Weight | 734.8 |
| Formula | C37H46N6O10 |
| Cas No. | 2785404-76-2 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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