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Anti-Phospho-ATF2 (Thr71) Antibody (3X852)
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Catalog No. TMAC-03192
Alias p-ATF2 (Thr71), p-ATF2 (T71), ATF2 (p-Thr71), ATF2 (p-T71)
Anti-Phospho-ATF2 (Thr71) Antibody (3X852) is a Rabbit antibody targeting Phospho-ATF2 (Thr71). Anti-Phospho-ATF2 (Thr71) Antibody (3X852) can be used in ICC/IF,IP,WB.
Anti-Phospho-ATF2 (Thr71) Antibody (3X852)
Anti-Phospho-ATF2 (Thr71) Antibody (3X852)
😃Good
Catalog No. TMAC-03192Alias p-ATF2 (Thr71), p-ATF2 (T71), ATF2 (p-Thr71), ATF2 (p-T71)
Anti-Phospho-ATF2 (Thr71) Antibody (3X852) is a Rabbit antibody targeting Phospho-ATF2 (Thr71). Anti-Phospho-ATF2 (Thr71) Antibody (3X852) can be used in ICC/IF,IP,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-ATF2 (Thr71) Antibody (3X852) is a Rabbit antibody targeting Phospho-ATF2 (Thr71). Anti-Phospho-ATF2 (Thr71) Antibody (3X852) can be used in ICC/IF,IP,WB. |
| Synonyms | p-ATF2 (Thr71), p-ATF2 (T71), ATF2 (p-Thr71), ATF2 (p-T71) |
| Ig Type | IgG |
| Clone | 3X852 |
| Reactivity | Human |
| Verified Activity | 1. ICC staining phospho-ATF2 (T71) in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. ICC staining phospho-ATF2 (T71) in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining phospho-ATF2 (T71) in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.    |
| Application | |
| Recommended Dose | WB: 1:1000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Eukaryotic gene transcription is regulated by sequence-specific transcription factors which bind modular cis-acting promotor and enhancer elements. The ATF/CREB transcription factor family binds the palindromic cAMP response element (CRE) octanucleotide TGACGTCA. The ATF/CREB family includes CREB-1, CREB-2 (also designated ATF-4), ATF-1, ATF-2 and ATF-3. This family of proteins contain highly divergent N-terminal domains, but share a C-terminal leucine zipper for dimerization and DNA binding. ATF-2 forms homodimers and heterodimers with c-Jun to initiate CRE-dependent transcription. Phosphorylation of ATF-2 at Thr 69 and Thr 71 by stress-activated kinases is necessary for transcriptional activation. Myc also induces phosphorylation of ATF-2 at Thr 69 and Thr 71 to prolong the half-life of ATF-2. ATF-2 also functions as a histone acetyltransferase (HAT) by specifically acetylating histones H2B and H4 in vitro. The gene encoding human ATF-2 maps to chromosome 2q31.1. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human ATF2 around the phosphorylation site of Thr71 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 55 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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