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Anti-CD16/FCGR3 Antibody-PE (1A938) is a PE-conjugated Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-PE (1A938) can be used in FCM.
Description | Anti-CD16/FCGR3 Antibody-PE (1A938) is a PE-conjugated Mouse antibody targeting CD16/FCGR3. Anti-CD16/FCGR3 Antibody-PE (1A938) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 1A938 |
Reactivity | Human |
Verified Activity | Flow cytometric analysis of Human CD16 expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD16. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
Application | FCM |
Recommended Dose | 5 μl/Test, 0.1 mg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD16a/Fc gamma RIIIa (rh CD16a/Fc gamma RIIIa; TMPY-00763; P08637-1; Met1-Gln208,176F) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
Purification | Protein A |
Appearance | Liquid |
Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
Research Background | Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes. |
Conjucates | PE |
Others Formats | Unconjugated/APC/PerCP/FITC |
Antibody Types Available | 5 |
Immunogen | Recombinant Human CD16a/Fc gamma RIIIa Protein (TMPY-00763) |
Antigen Species | Human |
Biology Area | Fc Receptors |
Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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