Adiponectin Protein, Human, Recombinant (hFc)

Name: Adiponectin Protein, Human, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-02848
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: GBP28, APM-1, APM1, ADPN, ADIPQTL1, adiponectin, C1Q and collagen domain containing, Adiponectin, ACRP30, ACDC) Copy Product Info

Synonyms: GBP28, APM-1, APM1, ADPN, ADIPQTL1, adiponectin, C1Q and collagen domain containing, Adiponectin, ACRP30, ACDC

Catalog No. TMPY-02848 Copy Product Info

Adiponectin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q15848.

Pack Size	Price	USA Stock	Global Stock
5 µg	$56	-	In Stock
10 µg	$88	-	In Stock
20 µg	$142	-	In Stock
50 µg	$276	-	In Stock
100 µg	$462	-	In Stock
200 µg	$787	7-10 days	7-10 days
500 µg	$1,680	7-10 days	7-10 days
1 mg	$2,950	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Bis-Tris PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Adiponectin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q15848.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q15848
Construction	A DNA sequence encoding the human ADIPOQ (Q15848) (Met1-Asn244) was expressed, fused with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Glu 19
Protein Purity	> 80 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	GBP28, APM-1, APM1, ADPN, ADIPQTL1, adiponectin, C1Q and collagen domain containing, Adiponectin, ACRP30, ACDC
Research Background	Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other tissues. Adiponectin mediates its actions in the periphery mainly via two receptors, AdipoR1 and AdipoR2. Adiponectin influences gonadotropin release, normal pregnancy, and assisted reproduction outcomes. Adiponectin, a beneficial adipokine, represents a major link between obesity and reproduction. Higher levels of adiponectin are associated with improved menstrual function and better outcomes in assisted reproductive cycles. Unlike other adipocytokines produced by adipose tissue, adiponectin appears to have anti-inflammatory, anti-diabetic, and anti-atherogenic properties. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways in a variety of cell types. The anti-inflammatory properties of adiponectin may be a major component of its beneficial effects on cardiovascular and metabolic disorders including atherosclerosis and insulin resistance. Additionally, it is important factor in chronic liver diseases and chronic kidney diseases. Some cancer cell types express adiponectin receptors. Thus Adiponectin may act on tumour cells directly by binding and activating adiponectin receptors and downstream signalling pathways.

Chemical Properties

Molecular Weight

51.6 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.