Calciseptin

Name: Calciseptin
Brand: TargetMol
SKU: T80078
Rating: 4.5 (1 reviews)

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Catalog No. T80078Cas No. 178805-91-9

Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It specifically targets and blocks L-type calcium channels [1].

Calciseptin

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Catalog No. T80078Cas No. 178805-91-9

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Product Introduction

Bioactivity

Description	Calciseptine, a neurotoxin isolated from the Black Mamba (Dendroaspis p. polylepis) venom, comprises 60 amino acids and is stabilized by four disulfide bonds. It specifically targets and blocks L-type calcium channels [1].
Targets&IC50	Ca2+ channel, L-type:15 nM

Chemical Properties

Molecular Weight	7036.12
Formula	C₂₉₉H₄₆₈N₉₀O₈₇S₁₀
Cas No.	178805-91-9

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

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