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Alpinetin (Alias: (-)-alpinetin)

Name: Alpinetin
Brand: TargetMol
SKU: T3867
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T3867 Copy Product Info

Purity: 98.39%

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Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-hepatoma and pancreatic cancer cells effects, by inhibiting proliferation , regulating of the Bcl-2 family and XIAP expression, releasing of cytochrome c and activating caspases.

Alpinetin

Copy Product Info

🥰Excellent

Catalog No. T3867

Alias (-)-alpinetin

Cas No. 36052-37-6

Pack Size	Price	USA Stock	Global Stock
5 mg	$30	In Stock	In Stock
10 mg	$50	In Stock	In Stock
25 mg	$96	In Stock	In Stock
50 mg	$139	In Stock	In Stock
100 mg	$198	In Stock	-
200 mg	$297	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$32	In Stock	In Stock

In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:98.39%

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Alpinetin AI Summary

Alpinetin shows cytotoxicity against human PANC1 cells, as assessed by cell viability testing, with a PC100 (concentration at which 100% cell viability is observed) greater than 256.0 μM. Additionally, Alpinetin inhibits FABP4, a fatty acid-binding protein involved in lipid metabolism and signaling pathways, at a concentration of 10 μM with an inhibition rate of 0.51%. This suggests potential implications for regulating lipid-related processes in the body..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-hepatoma and pancreatic cancer cells effects, by inhibiting proliferation , regulating of the Bcl-2 family and XIAP expression, releasing of cytochrome c and activating caspases.
Synonyms	(-)-alpinetin

Chemical Properties

Molecular Weight	270.28
Formula	C₁₆H₁₄O₄
Cas No.	36052-37-6
Smiles	COc1cc(O)cc2O[C@@H](CC(=O)c12)c1ccccc1
Relative Density.	1.284 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 49 mg/mL (181.29 mM), Sonication is recommended.

Chloroform, Dichloromethane, Ethyl Acetate, Acetone: Soluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.4 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6999 mL	18.4993 mL	36.9987 mL	184.9933 mL
5 mM	0.7400 mL	3.6999 mL	7.3997 mL	36.9987 mL
10 mM	0.3700 mL	1.8499 mL	3.6999 mL	18.4993 mL
20 mM	0.1850 mL	0.9250 mL	1.8499 mL	9.2497 mL
50 mM	0.0740 mL	0.3700 mL	0.7400 mL	3.6999 mL
100 mM	0.0370 mL	0.1850 mL	0.3700 mL	1.8499 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc