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Synonyms: S100a8, S100 calcium-binding protein A8, Protein S100-A8, Pro-inflammatory S100 cytokine, MRP-8, Mrp8, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, Chemotactic cytokine CP-10, Calgranulin-A, Caga

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $80 | 35 days | 35 days | |
| 10 μg | $129 | 35 days | 35 days | |
| 20 μg | $198 | 35 days | 35 days | |
| 50 μg | $390 | 35 days | 35 days | |
| 100 μg | $626 | 35 days | 35 days | |
| 200 μg | $987 | 35 days | 35 days | |
| 500 μg | $1,900 | 35 days | 35 days | |
| 1 mg | $2,730 | 35 days | 35 days |
| Description | Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. |
| Species | Rat |
| Expression System | E. coli |
| Tag | C-6xHis |
| Accession Number | P50115 |
| Amino Acid | Met1-Glu89 |
| Construction | Met1-Glu89 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, pH 8.0. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | S100a8, S100 calcium-binding protein A8, Protein S100-A8, Pro-inflammatory S100 cytokine, MRP-8, Mrp8, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, Chemotactic cytokine CP-10, Calgranulin-A, Caga |
| Research Background |
| Molecular Weight | 13 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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