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S100A8 Protein, Rat, Recombinant (His)

(Synonyms: S100a8, S100 calcium-binding protein A8, Protein S100-A8, Pro-inflammatory S100 cytokine, MRP-8, Mrp8, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, Chemotactic cytokine CP-10, Calgranulin-A, Caga) Copy Product Info

Synonyms: S100a8, S100 calcium-binding protein A8, Protein S100-A8, Pro-inflammatory S100 cytokine, MRP-8, Mrp8, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, Chemotactic cytokine CP-10, Calgranulin-A, Caga

Catalog No. TMPJ-00991 Copy Product Info
Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$8035 days35 days
10 μg$12935 days35 days
20 μg$19835 days35 days
50 μg$39035 days35 days
100 μg$62635 days35 days
200 μg$98735 days35 days
500 μg$1,90035 days35 days
1 mg$2,73035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis.
Species
Rat
Expression System
E. coli
TagC-6xHis
Accession NumberP50115
Amino AcidMet1-Glu89
ConstructionMet1-Glu89
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, pH 8.0.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsS100a8, S100 calcium-binding protein A8, Protein S100-A8, Pro-inflammatory S100 cytokine, MRP-8, Mrp8, Migration inhibitory factor-related protein 8, Leukocyte L1 complex light chain, Chemotactic cytokine CP-10, Calgranulin-A, Caga
Research Background
Chemical Properties
Molecular Weight13 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: S100A8 Protein, Rat, Recombinant (His) chemical structure | S100A8 Protein, Rat, Recombinant (His) molecular weight