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PAR650097
😃Good
Catalog No. T77402
Alias PAR650097, PAR 650097
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.
PAR650097
PAR650097
😃Good
Catalog No. T77402Alias PAR650097, PAR 650097
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $195 | - | In Stock | |
| 5 mg | $483 | - | In Stock | |
| 10 mg | $692 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,490 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.83% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research. |
| Targets&IC50 | PAR2 (human):0.58 nm, PAR2 (Ms):0.22 nM |
| In vitro | PAR650097 has a high affinity for human PAR2 with KD value =833 pM PAR650097 effectively inhibits trypsin-driven activation of PAR2 with IC50 of 0.58 or 0.22 nM, respectively. [1] |
| In vivo | Intravenous administration of PAR650097 (100 mg/kg for 7 days) in rats achieved systemic exposure equivalent to high multiples of IC50 in vitro. The half-life is about 1-2 days. [1] |
| Synonyms | PAR650097, PAR 650097 |
| Reactivity | Human |
| Verified Activity | Human F2RL1-his-P2A-EGFP-HEK293-A1 cells were stained with PAR650097 and negative control protein respectively, washed and then followed by PE and analyzed with FACS, and the EC50 is 0.03 μM.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PAR2 |
| Molecular Weight | 144.1 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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