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PAR650097

(Synonyms: PAR650097, PAR 650097) Copy Product Info
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Synonyms: PAR650097, PAR 650097

Catalog No. T77402 Copy Product Info
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PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.
PAR650097
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$156-In Stock
5 mg$386-In Stock
10 mg$553-In Stock
25 mg$863-In Stock
50 mgPreferential-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:98.83% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.
Targets & IC50
PAR2 (Ms):0.22 nM, PAR2 (human):0.58 nm
In vitro
PAR650097 effectively inhibits trypsin-driven activation of PAR2 with IC50 of 0.58 or 0.22 nM, respectively. [1]
In vivo
Intravenous administration of PAR650097 (100 mg/kg for 7 days) in rats achieved systemic exposure equivalent to high multiples of IC50 in vitro. The half-life is about 1-2 days. [1]
SynonymsPAR650097, PAR 650097
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetPAR2
Chemical Properties
Molecular Weight144.1 kDa
Smiles#N/A
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
StorageStore at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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Related Tags: PAR650097 chemical structure | PAR650097 in vivo | PAR650097 in vitro | PAR650097 molecular weight