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Synonyms: PAR650097, PAR 650097


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $156 | - | In Stock | |
| 5 mg | $386 | - | In Stock | |
| 10 mg | $553 | - | In Stock | |
| 25 mg | $863 | - | In Stock | |
| 50 mg | Preferential | - | In Stock |
| Description | PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research. |
| Targets & IC50 | PAR2 (Ms):0.22 nM, PAR2 (human):0.58 nm |
| In vitro | PAR650097 effectively inhibits trypsin-driven activation of PAR2 with IC50 of 0.58 or 0.22 nM, respectively. [1] |
| In vivo | Intravenous administration of PAR650097 (100 mg/kg for 7 days) in rats achieved systemic exposure equivalent to high multiples of IC50 in vitro. The half-life is about 1-2 days. [1] |
| Synonyms | PAR650097, PAR 650097 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PAR2 |
| Molecular Weight | 144.1 kDa |
| Smiles | #N/A |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Size | Quantity | Unit Price | Amount | Operation |
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