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Anti-LATS1 Polyclonal Antibody is a Rabbit antibody targeting LATS1. Anti-LATS1 Polyclonal Antibody can be used in ICC/IF.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $373 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-LATS1 Polyclonal Antibody is a Rabbit antibody targeting LATS1. Anti-LATS1 Polyclonal Antibody can be used in ICC/IF. |
Alias | WARTS protein kinase (h-warts), WARTS, Serine/threonine-protein kinase LATS1, LATS1, Large tumor suppressor homolog 1 |
Ig Type | IgG |
Reactivity | Human (predicted:Mouse,Rat,Chicken,Pig,Cow,Horse,Rabbit) |
Verified Activity | Hela cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (LATS1) polyclonal Antibody, Unconjugated (TMAB-01050) 1:25, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nucleus. |
Application | ICC/IF |
Recommended Dose | ICC/IF: 1:25 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cytoplasm, cytoskeleton, centrosome. Cytoplasm. Cytoplasm, cytoskeleton, spindle pole. |
Construction | Hybridoma Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Research Background | This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq]. |
Immunogen | KLH conjugated synthetic peptide: human LATS1 |
Antigen Species | Human |
Gene ID | |
Uniprot ID | |
Biology Area | Tumor suppressors,Kinases,Cytokinesis,Cdk Regulators |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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