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Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His)
(Synonyms: transferrin receptor) Copy Product InfoSynonyms: transferrin receptor
Catalog No. TMPY-03739 Copy Product Info
Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.5 kDa and the accession number is XP_005545315.1&NP_001244232.1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $48 | - | In Stock | |
| 10 µg | $75 | - | In Stock | |
| 20 µg | $118 | - | In Stock | |
| 50 µg | $229 | - | In Stock | |
| 100 µg | $386 | - | In Stock | |
| 200 µg | $682 | 7-10 days | 7-10 days | |
| 500 µg | $1,430 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:90%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Measured by its ability to neutralize transferrin-mediated proliferation of MCF-7 cells. The ED50 for this effect is typically 0.2-2μg/mL. |
| Description | Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.5 kDa and the accession number is XP_005545315.1&NP_001244232.1. |
| Species | Cynomolgus,Rhesus |
| Expression System | HEK293 Cells |
| Tag | N-His |
| Accession Number | XP_005545315.1&NP_001244232.1 |
| Construction | A DNA sequence encoding the cynomolgus/rhesus TFRC (XP_005545315.1/NP_001244232.1) (Cys89-Phe760) was expressed with a polyhistidine tag at the N-terminus. Cynomolgus and Rhesus TFRC sequences are identical. Predicted N terminal: His |
| Protein Purity | > 90 % as determined by SDS-PAGE  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | transferrin receptor |
| Research Background | Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system. TFRC / CD71 is regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. Up-regulated upon mitogenic stimulation. TFRC / CD71 represents a marker of malignant transformation in the pancreas that could be applied as potential diagnostic and therapeutic target. |
| Molecular Weight | 77.5 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) chemical structure | Transferrin Receptor/TFRC Protein, Cynomolgus, Rhesus, Recombinant (His) molecular weight
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