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p-Synephrine

Name: p-Synephrine
Brand: TargetMol
SKU: T8265
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Synonyms:

Catalog No. T8265 Copy Product Info

Purity: 99.78%

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p-Synephrine is a naturally occurring protoalkaloid used as a dietary supplement in the field of weight management. Mechanistically, compared to ephedrine and n-synephrine, p-synephrine exhibits weaker binding affinity for α-1, α-2, β-1, and β-2 adrenergic receptors at commonly used doses and does not demonstrate significant sympathomimetic activity. Furthermore, recent in vitro cellular studies have shown that p-Synephrine possesses antioxidant activity and exerts anti-inflammatory effects by downregulating the p38 MAPK/NF-κB signaling pathway.

Cas No. 614-35-7

Pack Size	Price	USA Stock	Global Stock
25 mg	$30	-	In Stock
50 mg	$40	-	In Stock
100 mg	$56	-	In Stock
1 mL x 10 mM (in DMSO)	$44	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.78%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	167.21
Formula	C₉H₁₃NO₂
Cas No.	614-35-7
Smiles	[C@@H](CNC)(O)C1=CC=C(O)C=C1
Relative Density.	1.159 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Store under nitrogen, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (598.05 mM), Sonication is recommended.

H2O: 1.6 mg/mL (9.57 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	5.9805 mL	29.9025 mL	59.8050 mL	299.0252 mL
5 mM	1.1961 mL	5.9805 mL	11.9610 mL	59.8050 mL

DMSO

	1mg	5mg	10mg	50mg
10 mM	0.5981 mL	2.9903 mL	5.9805 mL	29.9025 mL
20 mM	0.2990 mL	1.4951 mL	2.9903 mL	14.9513 mL
50 mM	0.1196 mL	0.5981 mL	1.1961 mL	5.9805 mL
100 mM	0.0598 mL	0.2990 mL	0.5981 mL	2.9903 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc