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Anti-CD69 Antibody-APC (9F511)

🥰Excellent
Catalog No. TMAY-01705A

Anti-CD69 Antibody-APC (9F511) is a APC-conjugated Mouse antibody targeting CD69. Anti-CD69 Antibody-APC (9F511) can be used in FCM.

Anti-CD69 Antibody-APC (9F511)

Anti-CD69 Antibody-APC (9F511)

🥰Excellent
Catalog No. TMAY-01705A
Anti-CD69 Antibody-APC (9F511) is a APC-conjugated Mouse antibody targeting CD69. Anti-CD69 Antibody-APC (9F511) can be used in FCM.
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Product Introduction

Bioactivity
Description
Anti-CD69 Antibody-APC (9F511) is a APC-conjugated Mouse antibody targeting CD69. Anti-CD69 Antibody-APC (9F511) can be used in FCM.
Ig Type
Monoclonal Mouse IgG1
Clone
9F511
Reactivity
Human
Verified Activity
Flow cytometric analysis of Human CD69 expression on PHA-activated human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human CD69. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes.
Application
FCM
Recommended Dose
5 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD69 (rh CD69; TMPY-01234; NP_001772.1; Ser62-Lys199) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundEarly activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/PerCP/FITC/PE
Antibody Types Available
5
Antigen Details
Immunogen
Recombinant Human CD69 Protein (TMPY-01234)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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