Anti-CD69 Antibody-APC (9F511)

Name: Anti-CD69 Antibody-APC (9F511)
Brand: TargetMol
SKU: TMAY-01705A
Rating: 4.5 (1 reviews)

(Synonyms: VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik) Copy Product Info

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Synonyms: VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik

Catalog No. TMAY-01705A Copy Product Info

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Anti-CD69 Antibody-APC (9F511) is a APC-conjugated Mouse antibody targeting CD69. Anti-CD69 Antibody-APC (9F511) can be used in FCM.

Pack Size	Price	USA Stock	Global Stock	Quantity
25 T	$81	7-10 days	7-10 days
100 T	$105	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Description	Anti-CD69 Antibody-APC (9F511) is a APC-conjugated Mouse antibody targeting CD69. Anti-CD69 Antibody-APC (9F511) can be used in FCM.
Synonyms	VEA, CD69 molecule, AIM, AI452015, 5830438K24Rik
Ig Type	Mouse IgG1
Clone	9F511
Reactivity	Human
Specificity	Human CD69

Application	FCM
Recommended Dose	5 μl/Test, 0.1 mg/ml
Antibody Type	Monoclonal
Host Species	Mouse
Construction	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD69 (rh CD69; TMPY-01234; NP_001772.1; Ser62-Lys199) and conjugated with APC under optimum conditions, the unreacted APC was removed.
Purification	Protein A
Appearance	Liquid
Formulation	PBS solution containing 0.5% BSA and 0.03%ProClin300
Research Background	Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients.