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Phenibut (hydrochloride)

🥰Excellent
Catalog No. T8639Cas No. 3060-41-1
Alias 3-Amino-4-phenylbutyric acid hydrochloride

Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine

Phenibut (hydrochloride)
Other Forms of Phenibut (hydrochloride):
PhenibutT29901078-21-3
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Phenibut (hydrochloride)

🥰Excellent
Purity: 99.93%
Catalog No. T8639Alias 3-Amino-4-phenylbutyric acid hydrochlorideCas No. 3060-41-1
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine
Pack SizePriceAvailabilityQuantity
25 mg$29In Stock
1 mL x 10 mM (in DMSO)$29In Stock
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Purity:99.93%
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Product Introduction

Bioactivity
Description
Phenibut hydrochloride (3-Amino-4-phenylbutyric acid hydrochloride) is a GABA mimetic that acts as an agonist at GABAB receptors, blocks α2δ subunit-containing voltage-gated calcium channels, stimulates dopamine receptors, and inhibits the actions of β-phenethylamine
Synonyms3-Amino-4-phenylbutyric acid hydrochloride
Chemical Properties
Molecular Weight215.68
FormulaC10H14ClNO2
Cas No.3060-41-1
SmilesCl.NCC(CC(O)=O)C1=CC=CC=C1
Relative Density.1.161g/cm3
ColorWhite
Appearancesolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (127.5 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.6365 mL23.1825 mL46.3650 mL231.8249 mL
5 mM0.9273 mL4.6365 mL9.2730 mL46.3650 mL
10 mM0.4636 mL2.3182 mL4.6365 mL23.1825 mL
20 mM0.2318 mL1.1591 mL2.3182 mL11.5912 mL
50 mM0.0927 mL0.4636 mL0.9273 mL4.6365 mL
100 mM0.0464 mL0.2318 mL0.4636 mL2.3182 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

γ-Aminobutyric acid Receptorβ-phenethylaminePhenibut (hydrochloride)PhenibutPEAneuropsychotropicInhibitorinhibitGamma-aminobutyric acid ReceptorGABAReceptorGABABGABA Receptorendogenousanxiogenic3-Amino-4-phenylbutyric acid Hydrochloride
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