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Anti-PRDM1 Antibody (4L235)

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Catalog No. TMAC-03412

Anti-PRDM1 Antibody (4L235) is a Mouse antibody targeting PRDM1. Anti-PRDM1 Antibody (4L235) can be used in WB,ICC,FCM.

Anti-PRDM1 Antibody (4L235)

Anti-PRDM1 Antibody (4L235)

😃Good
Catalog No. TMAC-03412
Anti-PRDM1 Antibody (4L235) is a Mouse antibody targeting PRDM1. Anti-PRDM1 Antibody (4L235) can be used in WB,ICC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4287-10 days
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Product Introduction

Bioactivity
Description
Anti-PRDM1 Antibody (4L235) is a Mouse antibody targeting PRDM1. Anti-PRDM1 Antibody (4L235) can be used in WB,ICC,FCM.
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; ICC: 1:200-1000; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe development and differentiation of plasma cells, which are terminally differentiated B-cells, are induced by Blimp-1 (B lymphocyte-induced maturation protein, also designated PRDI-BF1). Blimp-1 is a transcriptional repressor that localizes to the nucleus and is considered a master regulator of terminal B-cell development. Alone, Blimp-1 is sufficient to trigger terminal B-cell differentiation. Blimp-1 upregulates the expression of syndecan-1 and J chain, represses IFN-b gene transcription and associates with HDAC to recruit it to DNA, thereby repressing c-myc. Blimp-1 is expressed during the late stages of B-cell differentiation in immunoglobulin-secreting plasma cells, as well as in long-lived, bone marrow plasma cells. The expression of Blimp-1 defines a checkpoint beyond which fully activated B cells proceed to the plasma cell stage, whereas immature and partially activated cells are eliminated.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 92 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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