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PDGFB Protein, Canine, Recombinant (His)

(Synonyms: platelet-derived growth factor β polypeptide, platelet-derived growth factor beta polypeptide) Copy Product Info

Synonyms: platelet-derived growth factor β polypeptide, platelet-derived growth factor beta polypeptide

Catalog No. TMPY-05076 Copy Product Info
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q6Q7I7.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$987-10 days7-10 days
10 µg$1637-10 days7-10 days
20 µg$2737-10 days7-10 days
50 µg$6257-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Information

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q6Q7I7.
Species
Canine
Expression System
P. pastoris (Yeast)
TagN-His
Accession NumberQ6Q7I7
ConstructionA DNA sequence encoding the canine PDGFB (NP_001003383.1) (Ser82-Thr190) was expressed with a polyhistidine tag at the N-terminus. Predicted N terminal: His
Protein Purity
> 90 % as determined by SDS-PAGE.
EndotoxinPlease contact us for more information.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 30% CAN, 0.1% TFA. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonymsplatelet-derived growth factor β polypeptide, platelet-derived growth factor beta polypeptide
Research Background
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor.
Chemical Properties
Molecular Weight14.9 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: PDGFB Protein, Canine, Recombinant (His) chemical structure | PDGFB Protein, Canine, Recombinant (His) molecular weight