MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 86.00 | |
50 μg | 5 days | $ 262.00 | |
500 μg | 5 days | $ 2,150.00 | |
1 mg | 5 days | $ 3,220.00 |
Description | MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis. |
Species | Human |
Expression System | E. coli |
Tag | N-GST |
Accession Number | P46013 |
Synonyms | Ki-67, Antigen Ki67, MKI67, KIA, antigen KI-67, MIB-1, MIB-, Ki67, PPP1R105 |
Amino Acid | Met1-Pro120 |
Construction | Recombinant Human Proliferation Marker Protein Ki-67 is produced by our E.coli expression system and the target gene encoding Met1-Pro120 is expressed with a GST tag at the N-terminus. |
Protein Purity | Greater than 80% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 38 KDa, reducing conditions |
Endotoxin | Less than 1 EU/µg as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH 8.0. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis. |
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MKI67 Protein, Human, Recombinant (GST) PPP1R 105 PPP1R-105 Ki-67 Antigen Ki67 MKI 67 MKI67 KIA antigen KI-67 MIB-1 MIB- Ki67 MIB 1 PPP1R105 MKI-67 MIB1 recombinant recombinant-proteins proteins protein