MKI67 Protein, Human, Recombinant (GST)

Name: MKI67 Protein, Human, Recombinant (GST)
Brand: TargetMol
SKU: TMPJ-01436
Rating: 4.5 (1 reviews)

(Synonyms: PPP1R105, MKI67, MIB-1, MIB-, KIA, Ki-67, Ki67, antigen KI-67, Antigen Ki67) Copy Product Info

Synonyms: PPP1R105, MKI67, MIB-1, MIB-, KIA, Ki-67, Ki67, antigen KI-67, Antigen Ki67

Catalog No. TMPJ-01436 Copy Product Info

MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis.

Pack Size	Price	USA Stock	Global Stock
5 µg	$55	7-10 days	7-10 days
10 µg	$86	7-10 days	7-10 days
20 µg	$137	7-10 days	7-10 days
50 µg	$262	7-10 days	7-10 days
100 µg	$488	7-10 days	7-10 days
200 µg	$923	7-10 days	7-10 days
500 µg	$2,150	7-10 days	7-10 days
1 mg	$3,220	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis.
Species	Human
Expression System	E. coli
Tag	N-GST
Accession Number	P46013
Amino Acid	Met1-Pro120
Construction	Met1-Pro120
Protein Purity	Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 8% Sucrose, 0.05% Tween 80, pH 8.0.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	PPP1R105, MKI67, MIB-1, MIB-, KIA, Ki-67, Ki67, antigen KI-67, Antigen Ki67
Research Background	MKI67 also also known as Ki67, is a 350-400 kDa nuclear protein that belongs to a molecular group comprised of mitotic chromosome-associated proteins. MKI67 contains 1 FHA domain and plays a key role in cell proliferation. MKI67 is contextually expressed, being potentially found in all cells that are not in the Go phase of the cell cycle. Thus, MKI67 qualifies as a cell proliferation marker. It is also associated with ribosomal RNA transcription. Inactivation of antigen MKI67 leads to inhibition of ribosomal RNA synthesis.

Chemical Properties

Molecular Weight

38 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.