Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

L-Aspartic acid sodium (Synonyms: Disodium L-aspartate)

Name: L-Aspartic acid sodium
Brand: TargetMol
SKU: T65270
Rating: 4.5 (1 reviews)

Catalog No. T65270 Copy Product Info

Purity: 99.98%

😃Good

L-Aspartic acid sodium is the sodium salt form of the non-essential amino acid L-Aspartic acid that is employed to prepare polymeric carriers (e.g., poly(L-aspartic acid)) for prodrugs targeting colon and cecal tissues. Additionally, it is a key tool for investigating metabolic alterations in inflammatory conditions and studying its role as a metabolic hub hijacked by viruses, such as the enteric coronavirus PDCoV.

L-Aspartic acid sodium

Copy Product Info

😃Good

Catalog No. T65270

Synonyms Disodium L-aspartate

Cas No. 5598-53-8

Product information is being updated, if you want to purchase, please click the bulk custom button.

Add to Quotation

Questions

Batch Information

Select Batch

Purity:99.98%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	L-Aspartic acid sodium is the sodium salt form of the non-essential amino acid L-Aspartic acid that is employed to prepare polymeric carriers (e.g., poly(L-aspartic acid)) for prodrugs targeting colon and cecal tissues. Additionally, it is a key tool for investigating metabolic alterations in inflammatory conditions and studying its role as a metabolic hub hijacked by viruses, such as the enteric coronavirus PDCoV.
In vivo	L-Aspartic acid sodium serves as a colon-specific drug carrier, protecting drugs from degradation in the upper GI tract [1]. Additionally, the BBB actively effluxes L-Aspartic acid sodium (but not D-aspartic acid), reflecting tight regulation of excitatory amino acids in the CNS [2].
Synonyms	Disodium L-aspartate

Chemical Properties

Molecular Weight	177.07
Formula	C₄H₅NNa₂O₄
Cas No.	5598-53-8
Smiles	[O-]C(C[C@H](N)C([O-])=O)=O.[Na+].[Na+]

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 40.00 mg/mL (225.90 mM)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	5.6475 mL	28.2374 mL	56.4748 mL	282.3742 mL
5 mM	1.1295 mL	5.6475 mL	11.2950 mL	56.4748 mL
10 mM	0.5647 mL	2.8237 mL	5.6475 mL	28.2374 mL
20 mM	0.2824 mL	1.4119 mL	2.8237 mL	14.1187 mL
50 mM	0.1129 mL	0.5647 mL	1.1295 mL	5.6475 mL
100 mM	0.0565 mL	0.2824 mL	0.5647 mL	2.8237 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc