Anti-CYP2C9 Polyclonal Antibody

Name: Anti-CYP2C9 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-00524
Rating: 4.5 (1 reviews)

(Synonyms: S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase) Copy Product Info

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Synonyms: S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase

Catalog No. TMAB-00524 Copy Product Info

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Anti-CYP2C9 Polyclonal Antibody is a Rabbit antibody targeting CYP2C9. Anti-CYP2C9 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.

Anti-CYP2C9 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$221	7-10 days	7-10 days
100 μL	$374	7-10 days	7-10 days
200 μL	$529	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-CYP2C9 Polyclonal Antibody is a Rabbit antibody targeting CYP2C9. Anti-CYP2C9 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Synonyms	S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase
Ig Type	IgG
Reactivity	Mouse (predicted:Human,Rat)

Application	IF IHC-Fr IHC-P WB
Recommended Dose	WB: 1:500-2000; IHC-P: 1:200-800; IHC-Fr: 1:50-200; IF: 1:50-200
Antibody Type	Polyclonal
Host Species	Rabbit
Subcellular Localization	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human CYP2C9
Antigen Species	Human
Gene Name	CYP2C9
Gene ID	1559
Protein Name	Cytochrome P450 2C9
Uniprot ID	P11712
Biology Area	Cytochromes,Drug metabolism,Lipases,Cytochromes,Drug metabolism,Lipid metabolism
Function	Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S-warfarin, diclofenac, phenytoin, tolbutamide and losartan.