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Anti-CYP2C9 Polyclonal Antibody
😃Good
Catalog No. TMAB-00524
Alias S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase
Anti-CYP2C9 Polyclonal Antibody is a Rabbit antibody targeting CYP2C9. Anti-CYP2C9 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-CYP2C9 Polyclonal Antibody
Anti-CYP2C9 Polyclonal Antibody
😃Good
Catalog No. TMAB-00524Alias S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase
Anti-CYP2C9 Polyclonal Antibody is a Rabbit antibody targeting CYP2C9. Anti-CYP2C9 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CYP2C9 Polyclonal Antibody is a Rabbit antibody targeting CYP2C9. Anti-CYP2C9 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Alias | S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CYP2C9) Polyclonal Antibody, Unconjugated (TMAB-00524) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 min and DAB staining. 2. Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Mouse Stomach tissue lysates Primary: Anti-CYP2C9 (TMAB-00524) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kDa Observed band size: 52 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:200-800; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human CYP2C9 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cytochromes,Drug metabolism,Lipases,Cytochromes,Drug metabolism,Lipid metabolism |
| Molecular Weight | Theoretical: 56 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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