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2-Amino-5-chlorobenzophenone

Name: 2-Amino-5-chlorobenzophenone
Brand: TargetMol
SKU: T1685
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1685Cas No. 719-59-5

2-Amino-5-chlorobenzophenone is used as pharmaceutical intermediates.

2-Amino-5-chlorobenzophenone

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Purity: 99.42%

Catalog No. T1685Cas No. 719-59-5

2-Amino-5-chlorobenzophenone is used as pharmaceutical intermediates.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.42%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

2-Amino-5-chlorobenzophenone AI Summary

2-Amino-5-chlorobenzophenone exhibits a diverse range of bioactivities and demonstrates potent efficacy in multiple assays. It is involved in the identification of novel general anesthetics and inhibits chronic active B-cell receptor signaling, Histone Lysine Methyltransferase G9a, ELG1-dependent DNA repair, and Human Apurinic/apyrimidinic Endonuclease 1 (APE1). Moreover, it acts as an inverse agonist of the GLP-1 Receptor and an antagonist of cAMP-regulated guanine nucleotide exchange factor 2 (EPAC2). Additionally, 2-Amino-5-chlorobenzophenone shows antiviral activity against the Foot and Mouth Disease Virus. Furthermore, it exhibits antileishmanial activity against both Leishmania donovani promastigotes and amastigotes, with an IC50 value of 1.34 μg/mL for both strains. These multifaceted activities indicate the compound’s potential utility across various biological pathways and therapeutic targets..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

2-Amino-5-chlorobenzophenone is used as pharmaceutical intermediates.

Chemical Properties

Molecular Weight	231.68
Formula	C₁₃H₁₀ClNO
Cas No.	719-59-5
Smiles	NC1=C(C=C(Cl)C=C1)C(=O)C1=CC=CC=C1
Relative Density.	1.33 g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (237.4 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3163 mL	21.5815 mL	43.1630 mL	215.8149 mL
5 mM	0.8633 mL	4.3163 mL	8.6326 mL	43.1630 mL
10 mM	0.4316 mL	2.1581 mL	4.3163 mL	21.5815 mL
20 mM	0.2158 mL	1.0791 mL	2.1581 mL	10.7907 mL
50 mM	0.0863 mL	0.4316 mL	0.8633 mL	4.3163 mL
100 mM	0.0432 mL	0.2158 mL	0.4316 mL	2.1581 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc