Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

Pachypodol

🥰Excellent
Catalog No. TN2032Cas No. 33708-72-4

Pachypodol, a methoxyflavonoid isolated from Pogostemon cablin Bentham, has antioxidant and cytoprotective properties and inhibits the growth of CaCo 2 colon cancer cell lines in vitro.Pachypodol protects neonatal rats from anesthesia-induced apoptosis in the developing brain through modulation of the JNK/ERK pathway.PDGFRα kinase inhibitory activity in macrophages exposed to STING agonists.

Pachypodol

Pachypodol

🥰Excellent
Purity: 99.82%
Catalog No. TN2032Cas No. 33708-72-4
Pachypodol, a methoxyflavonoid isolated from Pogostemon cablin Bentham, has antioxidant and cytoprotective properties and inhibits the growth of CaCo 2 colon cancer cell lines in vitro.Pachypodol protects neonatal rats from anesthesia-induced apoptosis in the developing brain through modulation of the JNK/ERK pathway.PDGFRα kinase inhibitory activity in macrophages exposed to STING agonists.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$117-In Stock
5 mg$289-In Stock
10 mg$455-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.82%
Contact us for more batch information

Resource Download

COA CNMR HNMR HPLC MS

Product Introduction

Bioactivity
Description
Pachypodol, a methoxyflavonoid isolated from Pogostemon cablin Bentham, has antioxidant and cytoprotective properties and inhibits the growth of CaCo 2 colon cancer cell lines in vitro.Pachypodol protects neonatal rats from anesthesia-induced apoptosis in the developing brain through modulation of the JNK/ERK pathway.PDGFRα kinase inhibitory activity in macrophages exposed to STING agonists.
In vitro
Pachypodol, acting as a flavonol, is capable of inhibiting the growth of CaCo 2 colon cancer cell lines in vitro, and exhibits certain antioxidant and cytoprotective effects in HepG2 cells[1].
Chemical Properties
Molecular Weight344.32
FormulaC18H16O7
Cas No.33708-72-4
SmilesCOc1cc(O)c2c(c1)oc(-c1ccc(O)c(OC)c1)c(OC)c2=O
Relative Density.1.31g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (232.34 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9043 mL14.5214 mL29.0428 mL145.2138 mL
5 mM0.5809 mL2.9043 mL5.8086 mL29.0428 mL
10 mM0.2904 mL1.4521 mL2.9043 mL14.5214 mL
20 mM0.1452 mL0.7261 mL1.4521 mL7.2607 mL
50 mM0.0581 mL0.2904 mL0.5809 mL2.9043 mL
100 mM0.0290 mL0.1452 mL0.2904 mL1.4521 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PachypodolantioxidantAntifection
Related Tags: buy Pachypodol | purchase Pachypodol | Pachypodol cost | order Pachypodol | Pachypodol chemical structure | Pachypodol in vitro | Pachypodol formula | Pachypodol molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.