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2-Amino-6-bromopyridine

Name: 2-Amino-6-bromopyridine
Brand: TargetMol
SKU: T77347
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77347Cas No. 19798-81-3

2-Amino-6-bromopyridine has inhibitory effect on HIV-68 protease.

2-Amino-6-bromopyridine

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Purity: 99.98%

Catalog No. T77347Cas No. 19798-81-3

2-Amino-6-bromopyridine has inhibitory effect on HIV-68 protease.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.98%

Appearance:Solid

Color:Yellow

Resource Download

COA LCMS HNMR

Product Introduction

2-Amino-6-bromopyridine AI Summary

2-Amino-6-bromopyridine shows binding affinity to Pseudomonas aeruginosa PA14 PqsR, demonstrated by isothermal titration calorimetry with a Kd value of 10000.0 nM and surface plasmon resonance spectroscopy with a Kd value of 6800.0 nM. It exhibits agonist activity at PqsR, relative to PQS, at an activity level of 20.0% or less. Additionally, 2-Amino-6-bromopyridine acts as an antagonist by inhibiting PQS-induced protein activation with an activity of 22.0%..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

2-Amino-6-bromopyridine has inhibitory effect on HIV-68 protease.

Chemical Properties

Molecular Weight	173.01
Formula	C₅H₅BrN₂
Cas No.	19798-81-3
Smiles	NC1=NC(Br)=CC=C1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (346.8 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7800 mL	28.9001 mL	57.8001 mL	289.0006 mL
5 mM	1.1560 mL	5.7800 mL	11.5600 mL	57.8001 mL
10 mM	0.5780 mL	2.8900 mL	5.7800 mL	28.9001 mL
20 mM	0.2890 mL	1.4450 mL	2.8900 mL	14.4500 mL
50 mM	0.1156 mL	0.5780 mL	1.1560 mL	5.7800 mL
100 mM	0.0578 mL	0.2890 mL	0.5780 mL	2.8900 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc