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Anti-Lactoylglutathione lyase/GLO1 Antibody (8P849)

(Synonyms: S-D-lactoylglutathione methylglyoxal lyase, Methylglyoxalase, Lactoylglutathione lyase, Ketone-aldehyde mutase, Glyoxalase I (Glx I), GLO1, Aldoketomutase) Copy Product Info
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Synonyms: S-D-lactoylglutathione methylglyoxal lyase, Methylglyoxalase, Lactoylglutathione lyase, Ketone-aldehyde mutase, Glyoxalase I (Glx I), GLO1, Aldoketomutase

Catalog No. TMAC-01668 Copy Product Info
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Anti-Lactoylglutathione lyase/GLO1 Antibody (8P849) is a Rabbit antibody targeting Lactoylglutathione lyase/GLO1. Anti-Lactoylglutathione lyase/GLO1 Antibody (8P849) can be used in FCM,ICC,IHC,WB.
Anti-Lactoylglutathione lyase/GLO1 Antibody
(8P849)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Lactoylglutathione lyase/GLO1 Antibody (8P849) is a Rabbit antibody targeting Lactoylglutathione lyase/GLO1. Anti-Lactoylglutathione lyase/GLO1 Antibody (8P849) can be used in FCM,ICC,IHC,WB.
SynonymsS-D-lactoylglutathione methylglyoxal lyase, Methylglyoxalase, Lactoylglutathione lyase, Ketone-aldehyde mutase, Glyoxalase I (Glx I), GLO1, Aldoketomutase
Ig Type
IgG
Clone
8P849
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:100-500; ICC: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe glyoxal pathway plays a role in the detoxification of glucose degradation products (GDP). Glyoxalase I (GLO1), a member of the glyoxalase family, is effective in eliminating GDP. Overexpression or silencing of Glyoxalase I in mice brain suggests an association between Glyoxalase I and anxiety. Glyoxalase I has three isoforms generated from two alleles in the genome which forms two homodimers and one heterodimer, each subunit binding one zinc ion. Research demonstrates that GLO1 gene expression is induced in colon carcinoma. Both an insulin response element (IRE), and a zinc metal response element (MRE) in the promoter region of the GLO1 gene have been identified.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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