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Polyphyllin G

Name: Polyphyllin G
Brand: TargetMol
SKU: T3425
Rating: 4.5 (1 reviews)

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Catalog No. T3425Cas No. 76296-75-8

Alias Y-0166

Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocellular carcinoma and osteosarcoma.

Polyphyllin G

😃Good

Catalog No. T3425Alias Y-0166Cas No. 76296-75-8

Pack Size	Price	Availability
1 mg	$85	Backorder
5 mg	$207	Backorder
10 mg	$297	Backorder
25 mg	$577	Backorder
1 mL x 10 mM (in DMSO)	$349	In Stock

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Product Introduction

Bioactivity

Description	Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocellular carcinoma and osteosarcoma.
Targets&IC50	D. intermedius:1.2 mg/L(EC50)
Synonyms	Y-0166

Chemical Properties

Molecular Weight	1049.21
Formula	C₅₁H₈₄O₂₂
Cas No.	76296-75-8
Smiles	C1[C@@H](CC2=CC[C@@H]3[C@@H]([C@]2(C1)C)CC[C@]1([C@H]3C[C@H]2[C@@H]1[C@@H]([C@@](O2)(OC)CC[C@H](CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C)C)O[C@@H]1O[C@@H]([C@@H]([C@@H]([C@H]1O)OC1[C@@H]([C@@H]([C@H]([C@@H](O1)C)O)O)O)O[C@@H]1O[C@@H]([C@H]([C@@H]1O)O)CO)CO
Relative Density.	1.45 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95.3 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	0.9531 mL	4.7655 mL	9.5310 mL	47.6549 mL
5 mM	0.1906 mL	0.9531 mL	1.9062 mL	9.5310 mL
10 mM	0.0953 mL	0.4765 mL	0.9531 mL	4.7655 mL
20 mM	0.0477 mL	0.2383 mL	0.4765 mL	2.3827 mL
50 mM	0.0191 mL	0.0953 mL	0.1906 mL	0.9531 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc