Influenza A H7N9 (A/Anhui/1/2013) Matrix protein 1/M1 Protein (His)

The Influenza virus matrix protein 1 (M1) is a matrix protein of the influenza virus. M1 protein has been shown to play a crucial role in virus replication, assembly, and budding. It forms a coat inside the viral envelope. This is a bifunctional membrane/RNA-binding protein that mediates the encapsidation of RNA-nucleoprotein cores into the membrane envelope. M1 consists of two domains connected by a linker sequence. The N-terminal domain has a multi-helical structure. The C-terminal domain also contains an alpha-helical structure. The M1 protein is the most abundant structural protein in influenza A virus particles. M1 protein of the influenza A virus plays multiple roles in virion assembly and infection. M1 protein was a candidate antigen for a broad-spectrum influenza virus vaccine and the adjuvant chitosan significantly improved the efficacy of the M1 vaccine.

Pack Size	Availability	Price/USD	Quantity
100 μg	5 days	$ 801.00

Pack Size

Availability

Price/USD

Quantity

100 μg

5 days

$ 801.00

Description

Species	H7N9
Expression System	E. coli
Tag	His
Synonyms	cholinergic receptor, muscarinic 1
Construction	A DNA sequence encoding the Influenza A virus (A/Anhui/1/2013(H7N9)) Matrix protein 1 (EPI439506) (Met1-Lys252) was expressed with a C-terminal polyhistidine tag.
Protein Purity	> 85 % as determined by SDS-PAGE
Molecular Weight	Approxiamtely 28.5 kDa

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from sterile 20 mM tris, 0. 5 mM EDTA, 5% glycerol, 50 mM NaCl, pH 7.6. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution	A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage	Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background	The Influenza virus matrix protein 1 (M1) is a matrix protein of the influenza virus. M1 protein has been shown to play a crucial role in virus replication, assembly, and budding. It forms a coat inside the viral envelope. This is a bifunctional membrane/RNA-binding protein that mediates the encapsidation of RNA-nucleoprotein cores into the membrane envelope. M1 consists of two domains connected by a linker sequence. The N-terminal domain has a multi-helical structure. The C-terminal domain also contains an alpha-helical structure. The M1 protein is the most abundant structural protein in influenza A virus particles. M1 protein of the influenza A virus plays multiple roles in virion assembly and infection. M1 protein was a candidate antigen for a broad-spectrum influenza virus vaccine and the adjuvant chitosan significantly improved the efficacy of the M1 vaccine.

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Influenza A H7N9 (A/Anhui/1/2013) Matrix protein 1/M1 Protein (His)

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