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EphB4 Protein, Human, Recombinant (His), Biotinylated

(Synonyms: TYRO11, MYK1, HTK, EPH receptor B4) Copy Product Info

Synonyms: TYRO11, MYK1, HTK, EPH receptor B4

Catalog No. TMPY-05109 Copy Product Info
EphB4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P54760.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$1127-10 days7-10 days
10 µg$1837-10 days7-10 days
20 µg$3067-10 days7-10 days
50 µg$4927-10 days7-10 days
100 µg$8427-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
EphB4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P54760.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP54760
ConstructionA DNA sequence encoding the EPHB4 (NP_004435.3) (Met1-Ala539) was expressed with a C-terminal polyhistidine tag. The purified protein was biotinylated in vitro. Predicted N terminal: Leu 16
Protein Purity
> 95 % as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing Sterile PBS. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsTYRO11, MYK1, HTK, EPH receptor B4
Research Background
Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
Chemical Properties
Molecular Weight58.5 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: EphB4 Protein, Human, Recombinant (His), Biotinylated chemical structure | EphB4 Protein, Human, Recombinant (His), Biotinylated molecular weight