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Synonyms: RAGE, AGER, advanced glycosylation end product-specific receptor

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $68 | 7-10 days | 7-10 days | |
| 10 μg | $108 | 7-10 days | 7-10 days | |
| 20 μg | $178 | 7-10 days | 7-10 days | |
| 50 μg | $359 | 7-10 days | 7-10 days | |
| 100 μg | $696 | 7-10 days | 7-10 days | |
| 200 μg | $1,060 | 7-10 days | 7-10 days | |
| 500 μg | $2,230 | 7-10 days | 7-10 days | |
| 1 mg | $4,530 | 7-10 days | 7-10 days |
| Bioactivity | Measured by its binding ability in a functional ELISA. Immobilized human S100A12 at 2 μg/ml (100 μl/well) can bind recombinant human AGER with a linear range of 0.032-20 μg/ml. |
| Description | RAGE Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is A0A1U9X785. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q15109-1 |
| Construction | A DNA sequence encoding the human AGER isoform 1 (NP_001127.1) extracellular domain (Met 1-Ala 344) was fused with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gln 24 |
| Protein Purity | > 70 % as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | RAGE, AGER, advanced glycosylation end product-specific receptor |
| Research Background |
| Molecular Weight | 61.1 kDa (predicted); 80-90 kDa (reducing condition, due to glycosylation) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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