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Synonyms: Hypoxanthine-Guanine Phosphoribosyltransferase, HPRT1, HPRT, HGPRTase, HGPRT


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $183 | 7-10 days | 7-10 days | |
| 20 µg | $292 | 7-10 days | 7-10 days | |
| 50 µg | $545 | 7-10 days | 7-10 days | |
| 100 µg | $792 | 7-10 days | 7-10 days | |
| 200 µg | $1,150 | 7-10 days | 7-10 days | |
| 500 µg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed purine synthesis, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | P00492 |
| Amino Acid | Met1-Ala218 |
| Construction | Met1-Ala218 |
| Protein Purity | Greater than 85% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 250 mM NaCl, 50% Glycerol, pH8.0. |
| Synonyms | Hypoxanthine-Guanine Phosphoribosyltransferase, HPRT1, HPRT, HGPRTase, HGPRT |
| Research Background | Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed purine synthesis, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP. |
| Molecular Weight | 29 KDa (reducing condition) |
| Shipping | Proteins are shipped with blue ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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