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DLK1 Protein, Human, Recombinant (hFc)

Catalog No. TMPK-00921
Synonyms: DLK1, FA1, pG2, ZOG, secredeltin, DLK, Pref1, DLK-1

paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.

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DLK1 Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.
Species Human
Expression System HEK293
Tag C-hFc
Accession Number P80370-1
Synonyms DLK1, FA1, pG2, ZOG, secredeltin, DLK, Pref1, DLK-1
Construction Recombinant Human DLK1 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Ala24-Gln303.[Accession |P80370-1]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 56.58 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome.

References and Literature

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Keywords

DLK1 Protein, Human, Recombinant (hFc) DLK1 FA1 FA-1 pG2 ZOG DLK 1 secredeltin DLK Pref1 DLK-1 FA 1 recombinant recombinant-proteins proteins protein

 

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