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Anti-TNPO3 Antibody (8G85) is a Rabbit antibody targeting TNPO3. Anti-TNPO3 Antibody (8G85) can be used in ICC,IF,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
| Description | Anti-TNPO3 Antibody (8G85) is a Rabbit antibody targeting TNPO3. Anti-TNPO3 Antibody (8G85) can be used in ICC,IF,IHC,WB. |
| Synonyms | TRN-SR2, TRN-SR, TRNSR, TRN SR, Transportin-SR, Transportin-3, Transportin SR, Transportin 3, TNPO3_HUMAN, TNPO3, TNPO 3, MTR10A, IPO12, Importin-12, Importin 12, Imp12 |
| Ig Type | IgG |
| Clone | 8G85 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of TNPO3 on K562 cell (1), HL-60 cell (2) and mouse pancreas tissue (3) lysate using anti-TNPO3 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-TNPO3 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human small intestine tissue using anti-TNPO3 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-TNPO3 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-TNPO3 antibody. Counter stained with hematoxylin. 6. ICC staining TNPO3 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining TNPO3 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. ICC staining TNPO3 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Importin complex consists of Importin-α and Importin-β proteins which assist in transport of arginine- or serine-rich (SR) proteins across the nucleus. Importin-12, also known as Transportin-3 or Transportin-SR, is a member of the Importin-β family and functions as a nuclear transport receptor for serine/arginine-rich proteins. Through recognition of phosphorylated RS domains, Importin-12 mediates the nuclear import of several SR proteins, such as splicing factors SFRS1 and SFRS2. By regulating the nucleocytoplasmic transport of these and other SR mRNA splicing factors, Importin-12 controls their access to mRNA and, therefore, acts a transcriptional regulator. |
| Conjucates | Unconjugated |
| Uniprot ID |
| Molecular Weight | Theoretical: 104 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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