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Anti-TNPO3 Antibody (8G85) (Synonyms: TRN-SR2, TRN-SR, TRNSR, TRN SR, Transportin-SR, Transportin-3, Trans...)

Catalog No. TMAC-04075 Copy Product Info
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Anti-TNPO3 Antibody (8G85) is a Rabbit antibody targeting TNPO3. Anti-TNPO3 Antibody (8G85) can be used in ICC,IF,IHC,WB.

Anti-TNPO3 Antibody (8G85)

Copy Product Info
🥰Excellent
Catalog No. TMAC-04075
Synonyms TRN-SR2, TRN-SR, TRNSR, TRN SR, Transportin-SR, Transportin-3, Transportin SR, Transportin 3, TNPO3_HUMAN, TNPO3, TNPO 3, MTR10A, IPO12, Importin-12, Importin 12, Imp12

Anti-TNPO3 Antibody (8G85) is a Rabbit antibody targeting TNPO3. Anti-TNPO3 Antibody (8G85) can be used in ICC,IF,IHC,WB.

Anti-TNPO3 Antibody
(8G85)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TNPO3 Antibody (8G85) is a Rabbit antibody targeting TNPO3. Anti-TNPO3 Antibody (8G85) can be used in ICC,IF,IHC,WB.
SynonymsTRN-SR2, TRN-SR, TRNSR, TRN SR, Transportin-SR, Transportin-3, Transportin SR, Transportin 3, TNPO3_HUMAN, TNPO3, TNPO 3, MTR10A, IPO12, Importin-12, Importin 12, Imp12
Ig Type
IgG
Clone
8G85
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of TNPO3 on K562 cell (1), HL-60 cell (2) and mouse pancreas tissue (3) lysate using anti-TNPO3 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-TNPO3 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human small intestine tissue using anti-TNPO3 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-TNPO3 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-TNPO3 antibody. Counter stained with hematoxylin.
6. ICC staining TNPO3 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining TNPO3 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
8. ICC staining TNPO3 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
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Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Importin complex consists of Importin-α and Importin-β proteins which assist in transport of arginine- or serine-rich (SR) proteins across the nucleus. Importin-12, also known as Transportin-3 or Transportin-SR, is a member of the Importin-β family and functions as a nuclear transport receptor for serine/arginine-rich proteins. Through recognition of phosphorylated RS domains, Importin-12 mediates the nuclear import of several SR proteins, such as splicing factors SFRS1 and SFRS2. By regulating the nucleocytoplasmic transport of these and other SR mRNA splicing factors, Importin-12 controls their access to mRNA and, therefore, acts a transcriptional regulator.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 104 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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