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EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
(Synonyms: PIG61, NISBD2, mENA, LEGFR, HER1, ERBB1, ERBB, EGFR, EC 2.7.10.1, EC 2.7.10) Copy Product InfoSynonyms: PIG61, NISBD2, mENA, LEGFR, HER1, ERBB1, ERBB, EGFR, EC 2.7.10.1, EC 2.7.10
Catalog No. TMPK-00690 Copy Product Info
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.6 kDa and the accession number is NP_001333870.1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $148 | 7-10 days | 7-10 days | |
| 10 μg | $248 | 7-10 days | 7-10 days | |
| 20 μg | $415 | 7-10 days | 7-10 days | |
| 50 μg | $828 | 7-10 days | 7-10 days | |
| 100 μg | $1,400 | 7-10 days | 7-10 days | |
| 200 μg | $2,130 | 7-10 days | 7-10 days | |
| 500 μg | $3,720 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand. EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.6 kDa and the accession number is NP_001333870.1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His-Avi |
| Accession Number | NP_001333870.1 |
| Construction | Leu25-Ser378 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | PIG61, NISBD2, mENA, LEGFR, HER1, ERBB1, ERBB, EGFR, EC 2.7.10.1, EC 2.7.10 |
| Research Background |
| Molecular Weight | 41.6 kDa (predicted). Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result. |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled chemical structure | EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled molecular weight
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