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Cystatin B Protein, Mouse, Recombinant (His)

Catalog No. TMPJ-01174
Synonyms: PME, CST6cystatin B (liver thiol proteinase inhibitor)10STFBcystatin-B, cystatin B (stefin B), Cystatin B, EPM1, Stefin B, CPI-B, Liver thiol proteinase inhibitor, stefin-B, CSTB

Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as cathepsins B, H and L. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures.

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Cystatin B Protein, Mouse, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,970.00
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Biological Description
Technical Params
Product Properties
Description Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as cathepsins B, H and L. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures.
Species Mouse
Expression System E. coli
Tag N-6His
Accession Number Q62426
Synonyms PME, CST6cystatin B (liver thiol proteinase inhibitor)10STFBcystatin-B, cystatin B (stefin B), Cystatin B, EPM1, Stefin B, CPI-B, Liver thiol proteinase inhibitor, stefin-B, CSTB
Amino Acid Met1-Phe98
Construction Recombinant Mouse Cystatin-B is produced by our E.coli expression system and the target gene encoding Met1-Phe98 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 15 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.

Research Background Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases of the papain family such as cathepsins B, H and L. Defects in Cystatin-B / CSTB are the cause of progressive myoclonic epilepsy type 1 (EPM1) which is an autosomal recessive disorder characterized by severe, stimulus-sensitive myoclonus and tonic-clonic seizures.

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Keywords

Cystatin B Protein, Mouse, Recombinant (His) PME CST6cystatin B (liver thiol proteinase inhibitor)10STFBcystatin-B cystatin B (stefin B) Cystatin B EPM1 EPM 1 stefin B Stefin B CPI-B Liver thiol proteinase inhibitor stefin-B cystatin B EPM-1 CSTB recombinant recombinant-proteins proteins protein

 

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