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Anti-Aminopeptidase N/CD13 Antibody (3J107)
😃Good
Catalog No. TMAC-00653
Alias PEPN, p150, LAP1, GP150, CD13, APN, alanyl (membrane) aminopeptidase
Anti-Aminopeptidase N/CD13 Antibody (3J107) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (3J107) can be used in WB,ICC,IHC,IP.
Anti-Aminopeptidase N/CD13 Antibody (3J107)
Anti-Aminopeptidase N/CD13 Antibody (3J107)
😃Good
Catalog No. TMAC-00653Alias PEPN, p150, LAP1, GP150, CD13, APN, alanyl (membrane) aminopeptidase
Anti-Aminopeptidase N/CD13 Antibody (3J107) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (3J107) can be used in WB,ICC,IHC,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-Aminopeptidase N/CD13 Antibody (3J107) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (3J107) can be used in WB,ICC,IHC,IP. |
| Synonyms | PEPN, p150, LAP1, GP150, CD13, APN, alanyl (membrane) aminopeptidase |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of CD13 on different lysates using anti-CD13 antibody at 1/1,000 dilution. Positive control: Lane 1: THP-1, Lane 2: Human kidney. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD13 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-CD13 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-CD13 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-CD13 antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse pancreas tissue using anti-CD13 antibody. Counter stained with hematoxylin. 7. ICC staining CD13 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS 8. ICC staining CD13 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 9. ICC staining CD13 in PANC-1 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-5000; IHC: 1:100-500; ICC: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | CD13, or aminopeptidase N, is a type II transmembrane glycoprotein that is expressed on most cells of Myeloid origin, including monocytes, basophils, eosinophils, neutrophils and Myeloid leukemias. CD13 is also found on certain epithelial cells, fibroblasts and osteoclasts. CD13 acts as a zinc-binding metalloprotease that plays a role in digestion and may function in the inactivation of some regulatory peptides such as enkephalins. CD13 may play a role in the invasion of cancer cells by enhancing their invasive capacity and metastatic behavior. The activity of CD13 can be inactivated using specific inhibitors that evoke apoptosis of CD13-positive cancer cells. Basic fibroblast growth factor (bFGF) expression upregulates CD13 expression in human melanoma cells by activating both the Myeloid and the epithelial CD13 promoter. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 150 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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