Noggin/NOG Protein, Mouse, Recombinant (CHO)

Name: Noggin/NOG Protein, Mouse, Recombinant (CHO)
Brand: TargetMol
SKU: TMPS-00111
Rating: 4.5 (1 reviews)

(Synonyms: SYNS1A, SYNS1, SYM1, noggin, NOG) Copy Product Info

Synonyms: SYNS1A, SYNS1, SYM1, noggin, NOG

Catalog No. TMPS-00111 Copy Product Info

Noggin/NOG Protein, Mouse, Recombinant (CHO) is expressed in CHO Cells. The accession number is P97466.

Pack Size	Price	USA Stock	Global Stock
5 µg	$85	7-10 days	7-10 days
10 µg	$119	7-10 days	7-10 days
25 µg	$198	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Bioactivity

Bioactivity	ED 50 < 60.0 ng/ml, measured in a bioassay using ATDC5 cells in the presence of 10.0 ng/ml human BMP-4.
Description	Noggin/NOG Protein, Mouse, Recombinant (CHO) is expressed in CHO Cells. The accession number is P97466.
Species	Mouse
Expression System	CHO Cells
Tag	Tag Free
Accession Number	P97466
Construction	Leu20-Cys232
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SYNS1A, SYNS1, SYM1, noggin, NOG
Research Background	Noggin, also known as NOG, is a homodimeric glycoprotein that bindsto and modulates the activity of TGF-beta family ligands. It is expressed in condensing cartilage and immature chondrocytes. Noggin antagonizes bone morphogenetic protein (BMP) activities by blocking epitopes on BMPs needed for binding to their receptors. Noggin has been shown to be involved in many developmental processes, such as neural tube formation and joint formation. During development, Noggin diffuses through extracellular matrices and forms morphogenic gradients, regulating cellular responses dependent on the local concentration of the signaling molecule.

Chemical Properties

Molecular Weight

29~31 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.