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CTGF/CCN2 Protein, Human, Recombinant (HEK293, His)
(Synonyms: CTGF, Connective tissue growth factor) Copy Product InfoSynonyms: CTGF, Connective tissue growth factor
Catalog No. TMPJ-01163 Copy Product Info
Purity: 96%
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $55 | - | In Stock | |
| 10 μg | $86 | - | In Stock | |
| 20 μg | $137 | 35 days | 35 days | |
| 50 μg | $262 | 35 days | 35 days | |
| 100 μg | $488 | 35 days | 35 days | |
| 200 μg | $923 | 35 days | 35 days | |
| 500 μg | $2,150 | 35 days | 35 days | |
| 1 mg | $3,220 | 35 days | 35 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CYR61/CTGF/NOV) family of secreted matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF has various biological functions, including cell adhesion, migration, proliferation, differentiation, and ECM production, and participates in the development of many organs under normal physiologic conditions. CTGF is pathologically viewed as a central mediator of tissue remodeling and fibrosis of various organs, including the lung, heart, liver, and kidney. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | Q5M8T4 |
| Amino Acid | Gln27-Ala349 |
| Construction | Gln27-Ala349 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 300 mM NaCl, pH7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | CTGF, Connective tissue growth factor |
| Research Background |
| Molecular Weight | 33-45 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CTGF/CCN2 Protein, Human, Recombinant (HEK293, His) chemical structure | CTGF/CCN2 Protein, Human, Recombinant (HEK293, His) molecular weight
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