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Synonyms: WND/140 kDa, WND, Wilson disease associated protein, WD, WC1, tx, Toxic milk, PWD, Cu++ transporting, Cu(2+) transporting, Copper transporting ATPase 2, Copper pump 2, beta polypeptide, ATPase, ATP7B
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
| Description | Anti-ATP7B Antibody (4W208) is an antibody targeting ATP7B. Anti-ATP7B Antibody (4W208) can be used in ELISA,FCM,IF,IHC. |
| Synonyms | WND/140 kDa, WND, Wilson disease associated protein, WD, WC1, tx, Toxic milk, PWD, Cu++ transporting, Cu(2+) transporting, Copper transporting ATPase 2, Copper pump 2, beta polypeptide, ATPase, ATP7B |
| Ig Type | Rabbit IgG |
| Clone | 4W208 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC:1:50-1:200; IF:1:50-1:200; FCM:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Late endosome.; [Isoform 1]: Golgi apparatus membrane; Multi-pass membrane protein.; [Isoform 2]: Cytoplasm.; [WND/140 kDa]: Mitochondrion. |
| Tissue Specificity | Most abundant in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ATP7B |
| Antigen Species | Human |
| Gene Name | ATP7B |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Metabolism, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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