Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

S100B Protein, Mouse, Recombinant (His)

Name: S100B Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00990
Rating: 4.5 (1 reviews)

(Synonyms: S100b, S100 β, S-100 protein β chain, S-100 protein subunit β, S-100 protein subunit beta, S-100 protein beta chain, S100 calcium-binding protein B, S100 calcium binding protein B, S100 beta, Protein S100-B) Copy Product Info

Synonyms: S100b, S100 β, S-100 protein β chain, S-100 protein subunit β, S-100 protein subunit beta, S-100 protein beta chain, S100 calcium-binding protein B, S100 calcium binding protein B, S100 beta, Protein S100-B

Catalog No. TMPJ-00990 Copy Product Info

Purity: 99%

S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytes are the major cells producing S100-B protein in gray matter, as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop, enabling timely delivery of crucial medical intervention before irreversible damage occurs. In addition, S100-B, which is also present in Mouse melanocytes, is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.

Pack Size	Price	USA Stock	Global Stock
5 μg	$72	35 days	35 days
10 μg	$116	35 days	35 days
20 μg	$176	35 days	35 days
50 μg	$310	35 days	35 days
100 μg	$532	35 days	35 days
200 μg	$919	35 days	35 days
500 μg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:99%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity


Description	S100-B, is an acidic protein with a molecular weight of 21 kDa belonging to the S100 family. S100-B contains two EF-hand-type calcium-binding motifs separated by a hinge region with a hydrophobic cleft. S100-B plays an important role in neurodevelopment, differentiation, and brain construction. S100-B has neuroprotective effects, but at high concentrations S100-B is neurotoxic. Extracellular concentration of S100-B increases following brain damage, which easily penetrates into cerebrospinal fluid in brain damage and then into the blood. S100-B is expressed and produced by astrocytes in vertebrate brains and in the CNS, and the astrocytes are the major cells producing S100-B protein in gray matter, as well as oligodendrocytes are the predominant S100-B in protein producing cells in white matter. The major advantage of using S100-B is that elevations in serum or CSF levels provide a sensitive measure for determining CNS injury at the molecular level before gross changes develop, enabling timely delivery of crucial medical intervention before irreversible damage occurs. In addition, S100-B, which is also present in Mouse melanocytes, is a reliable marker for melanoma malignancy both in bioptic tissue and in serum.
Species	Mouse
Expression System	E. coli
Tag	C-6xHis
Accession Number	P50114
Amino Acid	Met1-Glu92
Construction	Met1-Glu92
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified) https://cdn.targetmol.com/group3/M00/3E/E2/CgoaEGbGogqEBtiXAAAAAAV7EB4368.png
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Synonyms	S100b, S100 β, S-100 protein β chain, S-100 protein subunit β, S-100 protein subunit beta, S-100 protein beta chain, S100 calcium-binding protein B, S100 calcium binding protein B, S100 beta, Protein S100-B
Research Background

Chemical Properties

Molecular Weight

12 KDa (reducing condition)

Storage & Solubility Information

Storage

Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

S-100 protein b chain

Related Tags: S100B Protein, Mouse, Recombinant (His) chemical structure | S100B Protein, Mouse, Recombinant (His) molecular weight