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Anti-HER3/ERBB3 Antibody-HRP (4Y273)
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Catalog No. TMAY-03517H
Alias erb-b2 receptor tyrosine kinase 3
Anti-HER3/ERBB3 Antibody-HRP (4Y273) is a HRP-conjugated Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody-HRP (4Y273) can be used in ELISA.
Anti-HER3/ERBB3 Antibody-HRP (4Y273)
Anti-HER3/ERBB3 Antibody-HRP (4Y273)
😃Good
Catalog No. TMAY-03517HAlias erb-b2 receptor tyrosine kinase 3
Anti-HER3/ERBB3 Antibody-HRP (4Y273) is a HRP-conjugated Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody-HRP (4Y273) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $411 | 7-10 days |
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| Description | Anti-HER3/ERBB3 Antibody-HRP (4Y273) is a HRP-conjugated Rabbit antibody targeting HER3/ERBB3. Anti-HER3/ERBB3 Antibody-HRP (4Y273) can be used in ELISA. |
| Alias | erb-b2 receptor tyrosine kinase 3 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4Y273 |
| Reactivity | Mouse |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse HER3 / ErbB3 (rM HER3 / ErbB3; TMPY-02365; Q61526; Met1-His641), and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin binding domain but has not an active kinase domain., and therefore can not mediate the intracellular signal transduction through protein phosphorylation. However, its heterodimer with ErbB2 or other EGFR members responsible for tyrosine phosphorylation forms a receptor complex with high affinity, and initiates the related pathway which lead to cell proliferation or differentiation. ErbB3 has been shown to implicated in numerous cancers, including prostate, bladder, and breast tumors. This protein has different isoforms derived from alternative splicing variants, and among which, the secreted isoform lacking the intermembrane region modulates the activity of membrane-bound form.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Mouse HER3 / ErbB3 protein (TMPY-02365) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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