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Anti-Phospho-mTOR (Ser2448) Antibody (2R744)
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Catalog No. TMAY-01376
Alias SKS, RAPT1, RAFT1, FRAP2, FRAP1, FRAP, FLJ44809
Anti-Phospho-mTOR (Ser2448) Antibody (2R744) is a Rabbit antibody targeting Phospho-mTOR (Ser2448). Anti-Phospho-mTOR (Ser2448) Antibody (2R744) can be used in WB.
Anti-Phospho-mTOR (Ser2448) Antibody (2R744)
Anti-Phospho-mTOR (Ser2448) Antibody (2R744)
😃Good
Catalog No. TMAY-01376Alias SKS, RAPT1, RAFT1, FRAP2, FRAP1, FRAP, FLJ44809
Anti-Phospho-mTOR (Ser2448) Antibody (2R744) is a Rabbit antibody targeting Phospho-mTOR (Ser2448). Anti-Phospho-mTOR (Ser2448) Antibody (2R744) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $80 | 7-10 days | |
| 100 μL | $233 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-mTOR (Ser2448) Antibody (2R744) is a Rabbit antibody targeting Phospho-mTOR (Ser2448). Anti-Phospho-mTOR (Ser2448) Antibody (2R744) can be used in WB. |
| Alias | SKS, RAPT1, RAFT1, FRAP2, FRAP1, FRAP, FLJ44809 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 2R744 |
| Reactivity | Human;
Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus; Predicted to React with:Phospho-mTOR (Ser2448); Species predicted to react based on 100% sequence homology: Mouse, Rat, Cynomolgus |
| Verified Activity | Western blot analysis of extracts from serum-starved HEK-293 treated without peptide (line A) or antigen-specific phosphopeptide (line B) or antigen-specific peptide (line C) using Phospho-mTOR (Ser2448) rabbit monoclonal Antibody at 1:5000 dilution. |
| Application | WB |
| Recommended Dose | WB: 1:2000-1:20000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around Ser2448 of Human Phospho-mTOR. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | MTOR (Mechanistic Target Of Rapamycin Kinase) is a Protein Coding gene. The protein encoded by the MTOR gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. MTOR is a central regulator of cellular metabolism, growth, and survival in response to hormones, growth factors, nutrients, energy, and stress signals. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. MTOR is broadly expressed in the testis, brain, and other tissues. Diseases associated with MTOR include Smith-Kingsmore Syndrome and Focal Cortical Dysplasia, Type Ii. The ANGPTL7 gene is located in an intron of this gene.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to the residues around Ser2448 of Human Phospho-mTOR |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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