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Anti-PLCγ1 Antibody (8G514)
(Synonyms: PLCy1, PLC-II, PLCgamma1, PLC148, PLC1, PLC γ1, PLC γ 1, PLC y1, PLC y 1, PLC gamma1, PLC gamma 1, NCKAP3, IDAA) Copy Product Info
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Synonyms: PLCy1, PLC-II, PLCgamma1, PLC148, PLC1, PLC γ1, PLC γ 1, PLC y1, PLC y 1, PLC gamma1, PLC gamma 1, NCKAP3, IDAA
Catalog No. TMAC-03370 Copy Product Info
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Anti-PLCγ1 Antibody (8G514) is a Mouse antibody targeting PLCγ1. Anti-PLCγ1 Antibody (8G514) can be used in FCM,ICC,IHC,WB.
Anti-PLCγ1 Antibody
(8G514)
(8G514)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $428 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-PLCγ1 Antibody (8G514) is a Mouse antibody targeting PLCγ1. Anti-PLCγ1 Antibody (8G514) can be used in FCM,ICC,IHC,WB. |
| Synonyms | PLCy1, PLC-II, PLCgamma1, PLC148, PLC1, PLC γ1, PLC γ 1, PLC y1, PLC y 1, PLC gamma1, PLC gamma 1, NCKAP3, IDAA |
| Clone | 8G514 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Phospholipase C-gamma 1 (PLC g1) is an isozyme of the phosphoinositide-specific PLC family, which occupies a central role in hormonal signal transduction pathways and is a substrate for the epidermal growth factor receptor tyrosine kinase. Following activation of TrkB, PLC g1 is phosphorylated on Tyrosine 783, Tyrosine 771 and Tyrosine 1253. Tyrosine 783 lies just downstream of the kinase domain in a relatively short sequence motif characteristic of the Trk family of protein-tyrosine kinase receptors. The sequence around Tyrosine 783 fits a consensus sequence for binding PLC g1. PLC g1 also forms a complex with TrkB consistent with the possibility that one of the TrkB autophosphorylation sites provides a binding site for the PLC g1 SH2 domains, as is the case for other receptor protein-tyrosine kinases. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 148 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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