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DiFMUP

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Catalog No. T31458Cas No. 214491-43-7
Alias 6,8-Difluoro-4-methylumbelliferyl phosphate

DiFMUP (6,8-Difluoro-4-methylumbelliferyl phosphate) inhibits protein tyrosine phosphatases (PTPs) and can be used to assay threonine phosphatase activity.

DiFMUP

DiFMUP

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Purity: 99.25%
Catalog No. T31458Alias 6,8-Difluoro-4-methylumbelliferyl phosphateCas No. 214491-43-7
DiFMUP (6,8-Difluoro-4-methylumbelliferyl phosphate) inhibits protein tyrosine phosphatases (PTPs) and can be used to assay threonine phosphatase activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$69-In Stock
5 mg$116-In Stock
10 mg$190-In Stock
25 mg$381-In Stock
50 mg$614-In Stock
100 mg$954-In Stock
1 mL x 10 mM (in DMSO)$127-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.25%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
DiFMUP (6,8-Difluoro-4-methylumbelliferyl phosphate) inhibits protein tyrosine phosphatases (PTPs) and can be used to assay threonine phosphatase activity.
Synonyms6,8-Difluoro-4-methylumbelliferyl phosphate
Chemical Properties
Molecular Weight292.13
FormulaC10H7F2O6P
Cas No.214491-43-7
SmilesO=C1OC=2C(F)=C(OP(=O)(O)O)C(F)=CC2C(=C1)C
Relative Density.1.716 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30 mg/mL (102.69 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.4231 mL17.1157 mL34.2313 mL171.1567 mL
5 mM0.6846 mL3.4231 mL6.8463 mL34.2313 mL
10 mM0.3423 mL1.7116 mL3.4231 mL17.1157 mL
20 mM0.1712 mL0.8558 mL1.7116 mL8.5578 mL
50 mM0.0685 mL0.3423 mL0.6846 mL3.4231 mL
100 mM0.0342 mL0.1712 mL0.3423 mL1.7116 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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